psychgirl
Has No Life - Lives on TB
Yay!
MNKYPOX Monkeypox - Consolidated Thread.
- Thread starter Tigerlily
- Start date
Tristan
Has No Life - Lives on TB
Over 50 and 'might be vacc'd'?
Should be in her records, right?
A call to the Doc would seem to be in order.
Last edited:
Tristan
Has No Life - Lives on TB
Tristan
Has No Life - Lives on TB
My take is when you begin looking for something, you begin finding it.
The timelines fit with BW's scenario, to a 'T'.
phloydius
Veteran Member
Those that are vaccinated when they are a child are not likely to remember it, especially if they were a toddler. And unless they were later told they may not even know. And although everyone I know shows a scar from it, she says that some people do not have scars (including her mother who was vaccinated). So maybe the word "might" may be valid?
Tristan
Has No Life - Lives on TB
jward
passin' thru
The WHO says monkeypox is not a global public health emergency
Leave a Comment / Health / By admin
The World Health Organization said on Saturday that the global monkeypox epidemic is not currently a public health emergency of international importance.
The WHO convened an emergency committee on Thursday to discuss whether the label, which has been given to only six outbreaks since 2007, is appropriate for monkeypox.
“The Emergency Committee has shared serious concerns about the scale and speed of the current epidemic,” WHO Director-General Tedros Adhanom Gebreyesus said in a statement.
“Overall, the report advised me that at this point, the event is not an emergency for public health of international importance, which is the highest level of concern that the WHO can issue,” he added.
The WHO said in another statement that the director general agreed with the commission’s board, although several members of the commission “expressed different views”.
The WHO maintains this type of emergency warning of “serious, sudden, unusual or unexpected” events that pose a health risk to more than one country and may require an immediate, coordinated international response. The organization has previously designated Covid-19, as well as Ebola, Zika, H1N1 flu and polio.
More than 4,000 cases of monkeypox have been reported worldwide in 47 countries and territories since early May, according to the Centers for Disease Control and Prevention. The United States alone registered more than 200 cases in 25 states and Washington, D.C., as of Friday.
Previously, monkeypox was largely limited in Africa, where it is endemic in 11 countries. Most monkeypox infections have been reported in the Democratic Republic of Congo, where more than 1,200 cases have been reported from January to May, according to the WHO.
The internationally spread version of the virus, the West African strain, has a mortality rate of 1%. No deaths have been reported outside Africa in connection with the current epidemic. The other, the Congo Basin strain, has a mortality rate of 10%.
The Director-General of the World Health Organization, Tedros Adanom Gebrejesus, at a press conference at the WHO headquarters in December 2021 in Geneva. Fabrice Coffrini / AFP via Getty Images file
“The Commission noted that many aspects of the current epidemic in several countries are unusual, such as the occurrence of cases in countries where the circulation of the monkeypox virus has not been previously documented, and the fact that the majority of cases occur. among men who have sex with young men, “the WHO said on Saturday.
Some members of the commission said there was a risk of “further, prolonged transmission to the general population”, the WHO added, given the low levels of immunity of the population.
Tedros said the commission could meet again “in the coming days and weeks” depending on how the outbreak develops. The Committee recommended that the outbreak be re-examined in a few weeks in order to observe major changes, such as a significant increase in the number of cases or evidence of a more severe or transmissible disease.
What do the symptoms of monkeypox look like?
The name monkeypox is misleading: although the virus was first discovered in laboratory monkeys in Denmark in 1958, it is much more common in small rodents.
Earlier this month, an international group of scientists called for the virus to be renamed to avoid discriminatory associations. Last week, Tedros said the WHO was working with experts to change the name of the virus, its strains and the disease it causes.
The organization also said that in the recent outbreak, many people “present with atypical symptoms”, including a localized rash with only one lesion.
Traditionally, patients with monkeypox develop flu-like symptoms such as fever and body aches, followed by a widespread rash, including on the face, hands and arms. But some recent patients report small bumps that look like a pimple or blister as the first or only symptom. Some patients develop flu-like symptoms later, while others do not.
Many recent cases have developed rashes around the genitals or anus, along with painful, swollen lymph nodes. CDC officials said last week that some patients in the United States reported pain in or around the anus and rectum, rectal bleeding, inflammation of the lining of the rectum, or a feeling that they needed bowel movements even though their bowels were empty.
Cases of monkeypox can look like chickenpox, herpes, or syphilis, so the CDC recommends that anyone who develops symptoms associated with these diseases be screened for monkeypox.
The virus appears to be spread mainly through sexual activity among men who have sex with men, but some cases have been reported in women. Anyone who has close physical contact with an infected person’s lesions or rashes, as well as through respiratory droplets and contaminated items such as clothing or bedding, can become infected.
The WHO said on Saturday that the emergency committee was concerned about “the rights to privacy, non-discrimination, physical and mental health of the affected groups, which will further hamper response efforts.”
What vaccines and treatments are there?
Smallpox and smallpox are orthopoxviruses, so smallpox vaccines can be used to prevent smallpox. In particular, an injection called Jynneos is specifically approved for use against monkeypox in Canada and the United States and is approved for off-label use in Europe.
The WHO does not currently recommend mass vaccination against monkeypox. Instead, he advises states to vaccinate close contacts of infected people, ideally within four days of exposure, which can prevent the onset of symptoms and disease. The WHO also recommends vaccines for healthcare workers who have been exposed to monkeypox and laboratory personnel who perform diagnostic tests for the virus.
New York opened a clinic on Thursday to vaccinate people who may have recently been exposed to monkeypox, including any gay, bisexual or other men who have sex with men “who have had multiple or anonymous sexual partners in the past 14 years.” days “. UK health officials also said earlier this week that doctors there could consider vaccinating some gay or bisexual men who are at higher risk of exposure, including men with multiple partners or who engage in group sex. .
“By extending the supply of vaccines to those at higher risk, we hope to break the transmission chain and help control the outbreak,” said Dr Mary Ramsey, head of immunization at the Health Security Agency. United Kingdom.
Doctors can also use antiviral drugs against smallpox and supportive care for monkeypox patients. Symptoms usually resolve after two to four weeks, although the lesions may leave scars.
The WHO advises infected people to isolate themselves until the scabs from any lesions “fall off and a new layer of skin forms.” He also recommended the use of condoms “to reduce the potential transmission of monkeypox, the risk of which is not yet known.”
escapefromwithin.com
Leave a Comment / Health / By admin
The World Health Organization said on Saturday that the global monkeypox epidemic is not currently a public health emergency of international importance.
The WHO convened an emergency committee on Thursday to discuss whether the label, which has been given to only six outbreaks since 2007, is appropriate for monkeypox.
“The Emergency Committee has shared serious concerns about the scale and speed of the current epidemic,” WHO Director-General Tedros Adhanom Gebreyesus said in a statement.
“Overall, the report advised me that at this point, the event is not an emergency for public health of international importance, which is the highest level of concern that the WHO can issue,” he added.
The WHO said in another statement that the director general agreed with the commission’s board, although several members of the commission “expressed different views”.
The WHO maintains this type of emergency warning of “serious, sudden, unusual or unexpected” events that pose a health risk to more than one country and may require an immediate, coordinated international response. The organization has previously designated Covid-19, as well as Ebola, Zika, H1N1 flu and polio.
More than 4,000 cases of monkeypox have been reported worldwide in 47 countries and territories since early May, according to the Centers for Disease Control and Prevention. The United States alone registered more than 200 cases in 25 states and Washington, D.C., as of Friday.
Previously, monkeypox was largely limited in Africa, where it is endemic in 11 countries. Most monkeypox infections have been reported in the Democratic Republic of Congo, where more than 1,200 cases have been reported from January to May, according to the WHO.
The internationally spread version of the virus, the West African strain, has a mortality rate of 1%. No deaths have been reported outside Africa in connection with the current epidemic. The other, the Congo Basin strain, has a mortality rate of 10%.
“The Commission noted that many aspects of the current epidemic in several countries are unusual, such as the occurrence of cases in countries where the circulation of the monkeypox virus has not been previously documented, and the fact that the majority of cases occur. among men who have sex with young men, “the WHO said on Saturday.
Some members of the commission said there was a risk of “further, prolonged transmission to the general population”, the WHO added, given the low levels of immunity of the population.
Tedros said the commission could meet again “in the coming days and weeks” depending on how the outbreak develops. The Committee recommended that the outbreak be re-examined in a few weeks in order to observe major changes, such as a significant increase in the number of cases or evidence of a more severe or transmissible disease.
What do the symptoms of monkeypox look like?
The name monkeypox is misleading: although the virus was first discovered in laboratory monkeys in Denmark in 1958, it is much more common in small rodents.
Earlier this month, an international group of scientists called for the virus to be renamed to avoid discriminatory associations. Last week, Tedros said the WHO was working with experts to change the name of the virus, its strains and the disease it causes.
The organization also said that in the recent outbreak, many people “present with atypical symptoms”, including a localized rash with only one lesion.
Traditionally, patients with monkeypox develop flu-like symptoms such as fever and body aches, followed by a widespread rash, including on the face, hands and arms. But some recent patients report small bumps that look like a pimple or blister as the first or only symptom. Some patients develop flu-like symptoms later, while others do not.
Many recent cases have developed rashes around the genitals or anus, along with painful, swollen lymph nodes. CDC officials said last week that some patients in the United States reported pain in or around the anus and rectum, rectal bleeding, inflammation of the lining of the rectum, or a feeling that they needed bowel movements even though their bowels were empty.
Cases of monkeypox can look like chickenpox, herpes, or syphilis, so the CDC recommends that anyone who develops symptoms associated with these diseases be screened for monkeypox.
The virus appears to be spread mainly through sexual activity among men who have sex with men, but some cases have been reported in women. Anyone who has close physical contact with an infected person’s lesions or rashes, as well as through respiratory droplets and contaminated items such as clothing or bedding, can become infected.
The WHO said on Saturday that the emergency committee was concerned about “the rights to privacy, non-discrimination, physical and mental health of the affected groups, which will further hamper response efforts.”
What vaccines and treatments are there?
Smallpox and smallpox are orthopoxviruses, so smallpox vaccines can be used to prevent smallpox. In particular, an injection called Jynneos is specifically approved for use against monkeypox in Canada and the United States and is approved for off-label use in Europe.
The WHO does not currently recommend mass vaccination against monkeypox. Instead, he advises states to vaccinate close contacts of infected people, ideally within four days of exposure, which can prevent the onset of symptoms and disease. The WHO also recommends vaccines for healthcare workers who have been exposed to monkeypox and laboratory personnel who perform diagnostic tests for the virus.
New York opened a clinic on Thursday to vaccinate people who may have recently been exposed to monkeypox, including any gay, bisexual or other men who have sex with men “who have had multiple or anonymous sexual partners in the past 14 years.” days “. UK health officials also said earlier this week that doctors there could consider vaccinating some gay or bisexual men who are at higher risk of exposure, including men with multiple partners or who engage in group sex. .
“By extending the supply of vaccines to those at higher risk, we hope to break the transmission chain and help control the outbreak,” said Dr Mary Ramsey, head of immunization at the Health Security Agency. United Kingdom.
Doctors can also use antiviral drugs against smallpox and supportive care for monkeypox patients. Symptoms usually resolve after two to four weeks, although the lesions may leave scars.
The WHO advises infected people to isolate themselves until the scabs from any lesions “fall off and a new layer of skin forms.” He also recommended the use of condoms “to reduce the potential transmission of monkeypox, the risk of which is not yet known.”
The WHO says monkeypox is not a global public health emergency - business
The World Health Organization said on Saturday that the global monkeypox epidemic is not currently a public health emergency of international importance.
escapefromwithin.com
Attachments
jward
passin' thru
WHO says monkeypox is not an international public health emergency, but it should continue to be monitored
Today, 05:10 PM
Source: https://www.cnn.com/2022/06/25/healt...ncy/index.html
WHO says monkeypox is not an international public health emergency, but it should continue to be monitored
By Carma Hassan, CNN
Updated 5:55 PM ET, Sat June 25, 2022
Monkeypox: Dr. Gupta explains how it spreads and what the symptoms are
Monkeypox: Dr. Gupta explains how it spreads and what the symptoms are 04:12
(CNN)The World Health Organization has stopped short of declaring the monkeypox outbreak a public health emergency of international concern as a result of an emergency committee meeting.
The WHO convened an emergency committee meeting Thursday to discuss the severity of the monkeypox outbreak. The result of the meeting was announced Saturday.
"Overall, in the report, they (the emergency committee) advised me that at this moment the event does not constitute a Public Health Emergency of International Concern, which is the highest level of alert WHO can issue but recognized that the convening of the committee itself reflects the increasing concern about the international spread of monkeypox," WHO Director-General Tedros Adhanom Ghebreyesus said in the statement released Saturday.
Tedros on Thursday called for intensified surveillance for monkeypox, cautioning that "while men who have sex with men have been most affected in these new outbreaks, there are also risks of severe disease for immunocompromised persons, pregnant women and children if they are infected."
Health care workers are also at risk if they don't wear appropriate personal protective equipment, Tedros said in his opening remarks at the meeting.
Last week, Tedros said "the virus is behaving unusually from how it used to behave in the past" and as more countries became affected, a coordinated response was necessary.
Saturday's statement acknowledged the "evolving health threat" that the WHO would be following extremely closely...
Today, 05:10 PM
Source: https://www.cnn.com/2022/06/25/healt...ncy/index.html
WHO says monkeypox is not an international public health emergency, but it should continue to be monitored
By Carma Hassan, CNN
Updated 5:55 PM ET, Sat June 25, 2022
Monkeypox: Dr. Gupta explains how it spreads and what the symptoms are
Monkeypox: Dr. Gupta explains how it spreads and what the symptoms are 04:12
(CNN)The World Health Organization has stopped short of declaring the monkeypox outbreak a public health emergency of international concern as a result of an emergency committee meeting.
The WHO convened an emergency committee meeting Thursday to discuss the severity of the monkeypox outbreak. The result of the meeting was announced Saturday.
"Overall, in the report, they (the emergency committee) advised me that at this moment the event does not constitute a Public Health Emergency of International Concern, which is the highest level of alert WHO can issue but recognized that the convening of the committee itself reflects the increasing concern about the international spread of monkeypox," WHO Director-General Tedros Adhanom Ghebreyesus said in the statement released Saturday.
Tedros on Thursday called for intensified surveillance for monkeypox, cautioning that "while men who have sex with men have been most affected in these new outbreaks, there are also risks of severe disease for immunocompromised persons, pregnant women and children if they are infected."
Health care workers are also at risk if they don't wear appropriate personal protective equipment, Tedros said in his opening remarks at the meeting.
Last week, Tedros said "the virus is behaving unusually from how it used to behave in the past" and as more countries became affected, a coordinated response was necessary.
Saturday's statement acknowledged the "evolving health threat" that the WHO would be following extremely closely...
bw
Fringe Ranger
Seriously? Making the court conservative and reversing Roe was foremost among the good things Trump was expected to do. My sisters were sweating out his election for exactly this reason. The people who wanted to reverse Roe were shopping for the right case to do it, and have watched those cases for years.
helen
Panic Sex Lady
This is Harbor Freight. I have no monetary interest in the company. I use one of these when I'm using cutting tools. It's very sturdy.
When combined with a paper face mask, the goggles become filled with water vapor in minutes. That was in freezing temperatures. I won't even try it in hot weather.
I saw something else that might work better.
When combined with a paper face mask, the goggles become filled with water vapor in minutes. That was in freezing temperatures. I won't even try it in hot weather.
I saw something else that might work better.
helen
Panic Sex Lady
This is Lowes version. Again, I have no connection to the company.
I have not tried it, but I talked to Lowes employees who were using these. They said the shields were comfortable enough.
Much less sturdy, but the goal is to keep spit (fomites) out of your eyes in public.
I have not tried it, but I talked to Lowes employees who were using these. They said the shields were comfortable enough.
Much less sturdy, but the goal is to keep spit (fomites) out of your eyes in public.
helen
Panic Sex Lady
You are on your own. You've been here before.
January 23, 2020.
View: https://twitter.com/RolandBakerIII/status/1540814345856114688?s=20
January 23, 2020.
View: https://twitter.com/RolandBakerIII/status/1540814345856114688?s=20
helen
Panic Sex Lady
Samuel Adams
Has No Life - Lives on TB
helen
Panic Sex Lady
Originally I thought getting monkeypox might confer some immunity to smallpox, should that ever get loose.
This monkeypox is not like the African strains I've watched for over 20 years. They are mutating and able to co-infect a patient. If it is goofed up like covid, we may never develop immunity to the next strain.
View: https://twitter.com/ahluv2/status/1541035998880079874?s=20
This monkeypox is not like the African strains I've watched for over 20 years. They are mutating and able to co-infect a patient. If it is goofed up like covid, we may never develop immunity to the next strain.
View: https://twitter.com/ahluv2/status/1541035998880079874?s=20
TxGal
Day by day
This is not directly related, but somehow it makes me wonder even more what the heck is going on - last evening I read an article that there is now an outbreak of what appears to be meningitis among gay men in Florida. I think there were over twenty cases.
And mostly gay men (originally) with Monkeypox.
And mostly gay men (originally) with Monkeypox.
We may be seeing a lot of "unexpected" outbreaks, due to the immune suppression from the COVID vaxx...
Summerthyme
TxGal
Day by day
That was pretty much my thought, too, Summerthyme.
Walkin' Away
Senior Member
TxGal & Summerthyme...add me to your list of "questioning why-ers"
Also, Psychgirl...check your local tractor supply company for Bag Balm...that's where I have found it.
W. A.
Also, Psychgirl...check your local tractor supply company for Bag Balm...that's where I have found it.
W. A.
TxGal
Day by day
Here's the article on meningitis among gay men from Zero Hedge (I don't want to derail the thread, though!):
CDC Investigating "Large, Ongoing" Outbreak Of Rare Disease In Florida | ZeroHedge
CDC Investigating "Large, Ongoing" Outbreak Of Rare Disease In Florida
BY TYLER DURDEN
SATURDAY, JUN 25, 2022 - 09:30 PM
Authored by Jack Phillips via The Epoch Times,
The U.S. Centers for Disease Control and Prevention (CDC) is investigating a “large, ongoing outbreak” of a rare disease in Florida.
In a press release, the CDC said Wednesday that meningococcal spread among homosexual males, including those with HIV, in the Florida outbreak.
The Florida Department of Health first issued an alert about an outbreak in Leon County several months ago.
...
Despite treatment, 10–15 in 100 people die of the disease, the agency says. Up to 20 percent of survivors may have long-term disabilities such as loss of limbs, deafness, brain damage, and problems with the central nervous system.
...
Read more here...
CDC Investigating "Large, Ongoing" Outbreak Of Rare Disease In Florida | ZeroHedge
CDC Investigating "Large, Ongoing" Outbreak Of Rare Disease In Florida
BY TYLER DURDEN
SATURDAY, JUN 25, 2022 - 09:30 PM
Authored by Jack Phillips via The Epoch Times,
The U.S. Centers for Disease Control and Prevention (CDC) is investigating a “large, ongoing outbreak” of a rare disease in Florida.
In a press release, the CDC said Wednesday that meningococcal spread among homosexual males, including those with HIV, in the Florida outbreak.
At least 24 cases and 6 deaths among homosexual males have been reported so far, according to the agency.
“Insurance providers should pay for meningococcal vaccination for those whom it is recommended for during an outbreak. In Florida, anyone can get a MenACWY vaccine at no cost at any county health department during the outbreak.”
The Florida Department of Health first issued an alert about an outbreak in Leon County several months ago.
...
Despite treatment, 10–15 in 100 people die of the disease, the agency says. Up to 20 percent of survivors may have long-term disabilities such as loss of limbs, deafness, brain damage, and problems with the central nervous system.
...
Read more here...
inskanoot
Veteran Member
Nicotine is highly addictive. About 10% of ingested nicotine comes out in the urine. I wonder if that version might be less addictive or otherwise more therapeutically beneficial. Not trying to gross anyone out, but there are some longstanding traditions that utilize otherwise toxic substances that are “clarified” in this fashion.So this new Franken pox has been obviously tweaked.... just like the covid. Say it with me..."gain of function"
Nicotine was shown to prevent covid infection.
"Daily active smokers are infrequent among outpatients or hospitalized patients with COVID-19. Several arguments suggest that nicotine is responsible for this protective effect via the nicotinic acetylcholine receptor (nAChR)."
CTG Labs - NCBI
clinicaltrials.gov
Biden just banned Vape... a super concentrated source of nicotine. I wonder if nicotine inhibits their new pox as well.
You must assume this new Franken pox is a binary weapon that will target those with covid vaxx.
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Me too. This is my thoughts as well.
psychgirl
Has No Life - Lives on TB
I’m of the belief that the gay male community is one of the most highly vaccinated demographics.
I just intuit that plus, I belong to two hobby groups that have a large number of gay members.
Most of them were going on and on about their vaxx status and how many they’d taken and boosted.
Several talked about their feeling poorly afterwards too.
Those gay men also seem to travel.
It all just “fits” the equation of damage in their immune systems, in my mind.
I just intuit that plus, I belong to two hobby groups that have a large number of gay members.
Most of them were going on and on about their vaxx status and how many they’d taken and boosted.
Several talked about their feeling poorly afterwards too.
Those gay men also seem to travel.
It all just “fits” the equation of damage in their immune systems, in my mind.
psychgirl
Has No Life - Lives on TB
I’m pretty sure I’ve seen it at cvs, and at Kroger too. Thank you!
Marseydoats
Veteran Member
I'm vaccinated and I don't have a scar. I don't know what my Dr. did differently, but none of the kids I grew up with that he vaccinated had scars either. I do remember that it hurt like hell and it itched...
inskanoot
Veteran Member
Re #3 for those who never had the smallpox vaccine, there is that nagging question: How much should you trust these folks?From Dr. Geert vanden Bossche
Open letter : Advice GVB
I am finalizing my analysis on the immune-epidemiologic consequences of the mass vaccination program. It will shed light on how the emergence of globally ongoing / starting epidemics of several different infectious diseases (meningococcal, TB, HIV, Herpetic diseases, etc.) as well as that of 2...voiceforscienceandsolidarity.substack.com
Open letter : Advice
Geert Vanden Bossche
2 hr ago
- I am finalizing my analysis on the immune-epidemiologic consequences of the mass vaccination program. It will shed light on how the emergence of globally ongoing / starting epidemics of several different infectious diseases (meningococcal, TB, HIV, Herpetic diseases, etc.) as well as that of 2 major pandemics (even if not yet officially declared as pandemics), i.e., Monkeypox and Avian Flu are related to the mass vax program.
Basically, the enhanced susceptibility of vaccinees to SC-2 (which results from their infection-enhancing vaccinal antibodies) sufficiently exhausts the innate and adaptive immune system to lower the population’s immune defense down to a level where these microorganisms can spread in the population. I will explain this in more detail but for now, I strongly advice all people who didn’t get the shot to:
- take extreme care of their health and lifestyle,
- not vaccinate against seasonal Influenza (!!) as this will only make you more susceptible to avian Flu (because of ADEI),
- for all those who didn’t get it in the past: get sooner or later the live attenuated, replication-competent smallpox vaccine (not yet available in sufficient supply but the expansion of smallpox is slower than that of avian Flu, so hope that this will allow for enough time to scale up production)
- make sure your young children do NOT get vaccinated with any of the C-19 vaccines (under no circumstances!) but get them properly vaccinated with the live attenuated childhood vaccines: Measles, mumps, rubella, varicella, as I predict that outbreaks will occur in countries / regions where herd immunity has dropped below the threshold
- not worry too much about C-19; most of us now have a level of trained innate immunity or even natural immunity that will protect us from moderate (and certainly from severe) disease. The situation will only further improve as the virus continues to select more resistant immune escape variants. I predict that even the unvaccinated vulnerable people will become less and less susceptible, but for now, some may still be vulnerable if they haven’t gotten any SC-2-infection experience yet.
- Avoid travel to other countries and follow the situation in your own region / country and also worldwide, especially re: avian influenza
- Consider removing your parents from the nursing home as we are up for outbreaks of RSV and seasonal Flu and having vulnerable people concentrated in the same place is just going to make it worse. Nevertheless, even the elderly and vulnerable people should stay away from seasonal Flu shots as they could be a death sentence if one gets hit by avian flu (ADEI!).
- As already mentioned, I strongly recommend all fully vaccinated people to ensure access to antivirals.
helen
Panic Sex Lady
You need to read this this whole thread. If you have access to Twitter, ask for a thread reader and post the whole thing. I'm banned for life there.
View: https://twitter.com/yaneerbaryam/status/1540831979071049728?s=20
View: https://twitter.com/yaneerbaryam/status/1540831979071049728?s=20
Cacheman
Ultra MAGA!
Thread by @yaneerbaryam on Thread Reader App
@yaneerbaryam: Old fashioned whodunit on smallpox transmission in Germany in 1970, perfect for weekend reading. Follow along as our heroes investigate. HT @jmcrookston 1/ "On 31 December 1969, a 20-year-old German e...…
threadreaderapp.com
Yaneer Bar-Yam
18h • 34 tweets • 7 min read
Old fashioned whodunit on smallpox transmission in Germany in 1970, perfect for weekend reading. Follow along as our heroes investigate.
HT @jmcrookston 1/
"On 31 December 1969, a 20-year-old German electrician flew to Dusseldorf from Karachi, West Pakistan, and then returned to his home in Meschede by train.
"On 10 January 1970, he developed fever and on the following day was hospitalized in Meschede.. 2/
"in an infectious diseases isolation ward, located on the ground floor of a 3-story building, one of several buildings of a large general hospital. He was confined to a private room within the isolation ward. Isolation precautions were observed from admission..3/
"On 14 January, a rash was first noticed and the following day smallpox was suspected. On 16 January the diagnosis was confirmed..
The patient was then transferred to a recently constructed smallpox isolation hospital..4/
"Despite the certainty that the original smallpox patient had not left his room during his hospitalization, all hospital patients and personnel were immunized as soon as the diagnosis of smallpox was made.5/
"The dates of onset of illness for all patients are shown graphically by date of onset of fever in Fig. 1; the two generations of the disease are indicated. Cases 19 and 20 clearly resulted from secondary spread within the hospital. 6/
The appearance of 17 cases of smallpox on three floors of the hospital during these second generation of disease was quite unexpected. 7/
"Three possible mechanisms of transmission have been considered: (1) direct personal contact; (2) contamination of fomites with resultant indirect spread of infection; (3) airborne spread. 8/
"The floor plan of the hospital building in which the outbreak occurred and the location of all cases is shown in Fig. 2. The location of individual cases is indicated by numbers which correspond to those in Table 1.. 9/
"The index patient had no direct face-to-face or personal contact with any of the subsequent patients. Interviews with the hospital staff and many of the other patients all confirmed the statement of the index patient that he did not leave his room at any.. 10/
"time following his admission.. until his transfer.. encased in a protective plastic garment.. Thus there was no possibility that direct contact with the index case could have explained the extensive spread of infection seen in the first generation of cases..11/
"The shape of the incidence curve (Fig.1) also exclude the possibility that an early secondary case in a nurse could have resulted in the extensive dissemination observed among the staff and patients.12/
"Transmission by contaminated fomites, while difficult to exclude entirely, seems most unlikely. None of the supplies or linen from [isolation ward on ground floor] R.1 were mixed with those of the upper floors or other parts of the hospital before,13/
"during or after hospitalization of the index patient and linen from the isolation unit..was separately disinfected before being washed. The absence of cases in the general hospital adjoining the isolation unit, despite sharing food-preparing and laundry.. 14/
"facilities and frequent movement of staff between the first and second floors of the isolation building and the main hospital building, suggests that contamination of linen, utensils and clothing did not play any role in transmission.15/
"The possibility was explored that a priest who routinely visited the patients might inadvertently have been a vector.. When the priest came to the door.. the day after admission, the priest was advised his services were not desired, and he did not again visit the patient..16/
"The most reasonable explanation for the spread of smallpox appears to be the airborne route. In addition to the fact that no alternative mechanisms of transmission could be elicited [see S. Holmes], two incidents and the distribution of cases 17/
within the hospital appear to confirm strongly this hypothesis.
"The first incident relates to the circumstances of the exposure of patient No. 8. It is certain that this patient had visited the hospital only once on the evening of 13 January.. 18/
and had remained in the building for 15 minutes.
"After entering the hospital by the front door he spoke briefly with a physician at the site designated "8" in Fig.2. As the hospital was closed to visitors, he was not permitted to enter the patient-care areas,. 19/
"nor did he enter the isolation unit corridor. Patient No. 8 had no known contact with any patient or any other member of the hospital staff but he subsequently developed typical smallpox with onset of fever on 24 January. 20/
"The second incident relates to..patient No. 15.. This patient..had been hospitalized for many months with severe arthritis and had not left her room for any purpose during the month of January.21/
"No hospital personnel other than the nuns, the priest, and physicians caring for the nuns were permitted to enter this area. This patient developed smallpox on 31 January.22/
"Additional strong support for the hypothesis of airborne transmission is the uniformity of attack rates by floor.. Such uniform rates would seem most unlikely if transfer of infection had occurred by direct contact or through fomites or indirectly.. 23/
"by hospital personnel, since the relative degree of flow pattern coincided closely with the distribution of exposure within the cloister, the other upper floors smallpox cases within the hospital. and the isolation unit was different for all items considered. 24/
"Since the airborne route seemed to be the method of transmission which would explain this incident most satisfactorily, patterns of air flow within the building were examined. Meteorological conditions on 10 April, a cold day selected for the test, were.. 25/
"similar to those of mid-January. A smoke-generating device was released in the room which had housed the index patient. The patterns of air currents observed inside and outside the buildings are shown approximately in Fig. 2; 26/
"the denser shading indicates a greater concentration of smoke. Within the building, dense smoke entered the corridor and rooms adjacent to that of the index patient. The smoke then passed down the corridor, through a door normally kept ajar by means of a special 27/
"device and then into the entrance hall. (Smallpox case No. 8 had waited in this entrance hall.) The smoke, after passing through this entrance area, flowed directly to the central stairwell which served effectively as a chimney and conducted a dense cloud 28/
"of smoke to the first and second floor levels where it drifted into the corridors and adjacent rooms. It is important to note that access to the upper units of the building involved passing through this stairwell area. 29/
The smoke from the index patient's room also flowed out of the partially opened window as a thin layer and then directly up the exterior surface of the building, as shown in Fig. 2. 30/
When windows were opened in the rooms above that occupied by the index patient, smoke readily entered these rooms. This flow pattern into the upper windows appeared to be caused by convection currents generated by radiators located below the windows. 31/
“It is interesting to note that the flow pattern coincided closely with the distribution of smallpox cases within the hospital. /32
Title gives it away: An Airborne Outbreak of Smallpox in a German Hospital
Note: Senior author is D. A. Henderson, WHO (see Wikipedia) 33/
ncbi.nlm.nih.gov/pmc/articles/P…
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427800/pdf/bullwho00209-0028.pdf
Here is the WHO of today removing smallpox from the list of airborne viruses 34/
View: https://twitter.com/mdc_martinus/status/1540228635101110272?ref_src=twsrc%5Etfw%7Ctwcamp%5Etweetembed%7Ctwterm%5E1540228635101110272%7Ctwgr%5E%7Ctwcon%5Es1_&ref_url=https%3A%2F%2Fthreadreaderapp.com%2Fthread%2F1540831979071049728.html
• • •
psychgirl
Has No Life - Lives on TB
Helen, that Martin guy you pointed to in that smallpox story??
Weird!
I was randomly surfing Twitter this morning, once I got past the way to do so without being a member…and also found his tweets!
Interesting stuff.
I think.
Anyway, there’s something very nefarious about the deleted information.
Weird!
I was randomly surfing Twitter this morning, once I got past the way to do so without being a member…and also found his tweets!
Interesting stuff.
I think.
Anyway, there’s something very nefarious about the deleted information.
Posted for fair use.....
nypost.com
Monkeypox spreading locally at large LA County events, health officials say
By Patrick Reilly
June 25, 2022 9:20pm Updated
MORE ON:MONKEYPOX
Most of the recent cases involve individuals who have not traveled out of the country or out of the state, as was the situation in most of the first identified cases in the US.
No hospitalizations or deaths have been reported, officials said.
“Anyone can get and spread monkeypox, but some of the recent cases identified have been among gay, bisexual, and other men who have sex with men who attended large events where the exposure to monkeypox may have occurred,” the Los Angeles Department of Public Health said in a statement on Friday. “Public Health is working with event organizers to notify attendees of potential exposure.”
The department said it would be JYNNEOS vaccine, targeting “individuals at higher risk of monkeypox,” which includes those who have had close contact with an infected person and those who were at an event where they may have had “skin-to-skin” contact with an infected person.
The department said it would be working to make the hard-to-come-by vaccine available for other high-risk groups as supplies increase.
SEE ALSO
Monkeypox mutates at unprecedented rate with ‘accelerated evolution,’ study finds
Monkeypox is a viral infection that causes skin lesions and is endemic in certain parts of Africa. But the current outbreak has hit countries like the US and United Kingdom where the virus does not usually spread, sparking global concern.
The virus can cause blisters, pimples and rashes on the skin. Most who contract monkeypox report only mild illness that goes away within two-to-four weeks without treatment.
Monkeypox can spread through contact of bodily fluids, monkeypox sores or clothing with an infected person, according to the Centers for Disease Control and Prevention. It can also be contracted by breathing in respiratory droplets while speaking to someone.
A handout picture made available by the UK Health Security Agency shows a collage of monkeypox rash lesions at an undisclosed date and location.UK Health Security Agency/AFP vi
The CDC said there have also been reports of transmission among family members and close contacts.
151
What do you think? Post a comment.
On Saturday, the US surpassed 200 confirmed cases nationwide, 51 of which are in California, according to the CDC’s latest data.
The White House announced earlier in the week that tests for the virus will be shipped to commercial laboratories to expand testing and speed up diagnoses.
Conversation 151 Comments
Monkeypox spreading locally at large LA County events, health officials say
On Saturday, the US surpassed 200 confirmed cases nationwide, 51 of which are in California, according to the CDC’s latest data.
nypost.com
Monkeypox spreading locally at large LA County events, health officials say
By Patrick Reilly
June 25, 2022 9:20pm Updated
MORE ON:MONKEYPOX
- NYC to run out of monkeypox vaccine by Monday, awaits Biden resupply
- Monkeypox mutates at unprecedented rate with ‘accelerated evolution,’ study finds
- Health officials scramble to ramp up monkeypox testing amid increasing demand
- UK to offer monkeypox vaccines to some gay and bisexual men
Most of the recent cases involve individuals who have not traveled out of the country or out of the state, as was the situation in most of the first identified cases in the US.
No hospitalizations or deaths have been reported, officials said.
“Anyone can get and spread monkeypox, but some of the recent cases identified have been among gay, bisexual, and other men who have sex with men who attended large events where the exposure to monkeypox may have occurred,” the Los Angeles Department of Public Health said in a statement on Friday. “Public Health is working with event organizers to notify attendees of potential exposure.”
The department said it would be JYNNEOS vaccine, targeting “individuals at higher risk of monkeypox,” which includes those who have had close contact with an infected person and those who were at an event where they may have had “skin-to-skin” contact with an infected person.
The department said it would be working to make the hard-to-come-by vaccine available for other high-risk groups as supplies increase.
SEE ALSO
Monkeypox mutates at unprecedented rate with ‘accelerated evolution,’ study finds
Monkeypox is a viral infection that causes skin lesions and is endemic in certain parts of Africa. But the current outbreak has hit countries like the US and United Kingdom where the virus does not usually spread, sparking global concern.
The virus can cause blisters, pimples and rashes on the skin. Most who contract monkeypox report only mild illness that goes away within two-to-four weeks without treatment.
Monkeypox can spread through contact of bodily fluids, monkeypox sores or clothing with an infected person, according to the Centers for Disease Control and Prevention. It can also be contracted by breathing in respiratory droplets while speaking to someone.
A handout picture made available by the UK Health Security Agency shows a collage of monkeypox rash lesions at an undisclosed date and location.UK Health Security Agency/AFP viThe CDC said there have also been reports of transmission among family members and close contacts.
151
What do you think? Post a comment.
On Saturday, the US surpassed 200 confirmed cases nationwide, 51 of which are in California, according to the CDC’s latest data.
The White House announced earlier in the week that tests for the virus will be shipped to commercial laboratories to expand testing and speed up diagnoses.
Conversation 151 Comments
Old Gray Mare
TB Fanatic
Wondering how much residual protection, if any, is had from smallpox vaccinations? Any reports at all of vaccinated getting monkey pox like ever? Would it be totally ironic if this only effects those not vaccinated?
Ordinary Girl
Veteran Member
Case number increase will be in the hundreds tomorrow
Meemur
Voice on the Prairie / FJB!
Yikes!
Tristan
Has No Life - Lives on TB
A very good question.
I wonder if any Scientists have tested that before?
If you trust the CDC, they say: "Past data from Africa suggests that the smallpox vaccine is at least 85% effective in preventing monkeypox."
Of course, it's being acknowledged that this is basically a New-and-Improved MP, at least according to some posts I've read...
There should be a pretty significant data pool from Great Britain, Spain and Portugal to review, should anyone in a position to actually have the data had an interest...
jward
passin' thru
First confirmed case of Monkeypox in a child in Île-de-France
Press release - English Google Translate [/B][/SIZE]
Today, 09:39 PM
25 juin 2022
The Île-de-France Regional Health Agency (ARS) informs of the occurrence of a first confirmed case of monkeypox (monkey pox) in a child attending primary school in the region. He was taken care of and shows no signs of seriousness.
The ARS Île-de-France and the teams of Public Health France immediately began the investigations in order to trace the chain of contacts of the child as quickly as possible. A probable case has been identified within the same siblings. Measures have been taken with National Education and a message has been sent to the parents of children who are at-risk contacts at the school attended by the child, in order to follow the following recommendations:
Monitor the appearance of symptoms (fever, rash) and call 15 if necessary;
Be offered a consultation in order to have the child benefit from a vaccination if it is deemed necessary by the doctor;
In the absence of symptoms, and in the state of knowledge, there is no known risk of contagion. No measures are therefore necessary for the child (neither isolation nor adaptation of activities) or for other family members.
This is the first confirmed case of Monkeypox in a child in France; the virus had previously only affected adults (330 cases confirmed by Santé Publique France as of June 23 at 2 p.m., including 227 in Île-de-France)
The characteristics and the contagiousness of this disease mean that it can also affect children in a family setting by sharing linens, living rooms, cutlery, in particular. This is the case in some countries where this virus is endemic and where transmission can occur through close contact with a person who shows signs of the disease (rash in the form of “pimples”). The risk of transmission, for the general population, is assessed as low.
The cases reported in France and Europe have so far occurred mainly in young adults, and are benign.
From the start of the epidemic, the health authorities anticipated the appearance of the virus in children in order to be able to prevent it and take care of confirmed cases through recommendations adapted from the Haute Autorité de Santé (HAS) and Haut Public Health Council (HCSP).
Premier cas confirmé de Monkeypox chez un enfant en Île-de-France
Communiqué de presse
25 juin 2022
L’Agence Régionale de Santé (ARS) Île-de-France informe de la survenue d’un premier cas confirmé de monkeypox (variole du singe) chez un enfant scolarisé en école primaire, dans la région. Il a été pris en charge et ne présente aucun signe de gravité. ...
https://www.iledefrance.ars.sante.fr...-ile-de-france
[/B][/B]
Press release - English Google Translate [/B][/SIZE]
Today, 09:39 PM
25 juin 2022
The Île-de-France Regional Health Agency (ARS) informs of the occurrence of a first confirmed case of monkeypox (monkey pox) in a child attending primary school in the region. He was taken care of and shows no signs of seriousness.
The ARS Île-de-France and the teams of Public Health France immediately began the investigations in order to trace the chain of contacts of the child as quickly as possible. A probable case has been identified within the same siblings. Measures have been taken with National Education and a message has been sent to the parents of children who are at-risk contacts at the school attended by the child, in order to follow the following recommendations:
Monitor the appearance of symptoms (fever, rash) and call 15 if necessary;
Be offered a consultation in order to have the child benefit from a vaccination if it is deemed necessary by the doctor;
In the absence of symptoms, and in the state of knowledge, there is no known risk of contagion. No measures are therefore necessary for the child (neither isolation nor adaptation of activities) or for other family members.
This is the first confirmed case of Monkeypox in a child in France; the virus had previously only affected adults (330 cases confirmed by Santé Publique France as of June 23 at 2 p.m., including 227 in Île-de-France)
The characteristics and the contagiousness of this disease mean that it can also affect children in a family setting by sharing linens, living rooms, cutlery, in particular. This is the case in some countries where this virus is endemic and where transmission can occur through close contact with a person who shows signs of the disease (rash in the form of “pimples”). The risk of transmission, for the general population, is assessed as low.
The cases reported in France and Europe have so far occurred mainly in young adults, and are benign.
From the start of the epidemic, the health authorities anticipated the appearance of the virus in children in order to be able to prevent it and take care of confirmed cases through recommendations adapted from the Haute Autorité de Santé (HAS) and Haut Public Health Council (HCSP).
Premier cas confirmé de Monkeypox chez un enfant en Île-de-France
Communiqué de presse
25 juin 2022
L’Agence Régionale de Santé (ARS) Île-de-France informe de la survenue d’un premier cas confirmé de monkeypox (variole du singe) chez un enfant scolarisé en école primaire, dans la région. Il a été pris en charge et ne présente aucun signe de gravité. ...
https://www.iledefrance.ars.sante.fr...-ile-de-france
[/B][/B]
jward
passin' thru
Monkeypox may have undergone 'accelerated evolution,' scientists say [/B][/SIZE]
Today, 01:39 PM
1 day ago
By Ben Turner
The virus is mutating up to 12 times faster than expected.
... As a large double-stranded DNA virus, monkeypox is much more able to correct replication errors than an RNA virus such as HIV, meaning that the current monkeypox strain should have really only accumulated a handful of mutations since it first started circulating in 2018. But, after collecting DNA from 15 monkeypox viral samples and reconstructing their genetic information, the researchers found that the real mutation rate was six to 12 times higher than they expected.
The massive jump in the monkey virus's rate of mutation "is far more than one would expect considering previous estimates of the substitution rate for Orthopoxviruses," the researchers wrote in the paper. "Our data reveals additional clues of ongoing viral evolution and potential human adaptation."
Historically, monkeypox is transmitted from person to person by close skin contact with open skin lesions, bodily fluids, contaminated material or respiratory droplets coughed into the air. But the unprecedented speed of new infections could suggest that something may have changed about how the virus infects its hosts — and the new mutations could be a possible cause.
Many of the mutations identified by the researchers also carry telltale clues that they may have emerged due to the virus's contact with the human immune system, specifically a family of the virus-fighting enzymes called APOBEC3. These enzymes attack viruses by forcing them to make mistakes when they copy their genetic code, an act which usually causes the virus to break apart.
Monkeypox may have undergone 'accelerated evolution,' scientists say[/B][/B]
Today, 01:39 PM
1 day ago
By Ben Turner
The virus is mutating up to 12 times faster than expected.
... As a large double-stranded DNA virus, monkeypox is much more able to correct replication errors than an RNA virus such as HIV, meaning that the current monkeypox strain should have really only accumulated a handful of mutations since it first started circulating in 2018. But, after collecting DNA from 15 monkeypox viral samples and reconstructing their genetic information, the researchers found that the real mutation rate was six to 12 times higher than they expected.
The massive jump in the monkey virus's rate of mutation "is far more than one would expect considering previous estimates of the substitution rate for Orthopoxviruses," the researchers wrote in the paper. "Our data reveals additional clues of ongoing viral evolution and potential human adaptation."
Historically, monkeypox is transmitted from person to person by close skin contact with open skin lesions, bodily fluids, contaminated material or respiratory droplets coughed into the air. But the unprecedented speed of new infections could suggest that something may have changed about how the virus infects its hosts — and the new mutations could be a possible cause.
Many of the mutations identified by the researchers also carry telltale clues that they may have emerged due to the virus's contact with the human immune system, specifically a family of the virus-fighting enzymes called APOBEC3. These enzymes attack viruses by forcing them to make mistakes when they copy their genetic code, an act which usually causes the virus to break apart.
Monkeypox may have undergone 'accelerated evolution,' scientists say[/B][/B]