somewherepress
Has No Life - Lives on TB
Not the wrong thread. Read the post.
MNKYPOX Monkeypox - Consolidated Thread.
- Thread starter Tigerlily
- Start date
Still 0.0003% of world population.
phloydius
Veteran Member
Hum... seems your right. Sorry.
phloydius
Veteran Member
On 4th February 2020, there were only 23,899 cases of Covid-19. Today there has been over 575 million (officially).
People who are into preparedness generally try to look to what is going on to see where things might go in the future to prepare for them. Just because there are only 25,628 cases today, does not mean there won't be 1,000,000+ cases by December 31st... and how many will there be by the end of 2023?
Monkeypox is not spreading as fast as Covid-19, but it is spreading fast.
SouthernBreeze
Has No Life - Lives on TB
While what you said is true, I saw DHR43's comment as a statement of fact, not as one of contention.
Tristan
Has No Life - Lives on TB
Cascadians
Leska Emerald Adams
Yes.
phloydius
Veteran Member
I think I may be a bit grumpy this morning. I did not take DHR43's statement as one of contention, but I did take it as a "there is nothing to see here" sort of comment. After looking at DHR43's other posts, I may be reading in some of my own frustration today into thier post. Based on your post, it sounds like my post is coming off as contentious -- which was not my intent. DHR43, if my post is offensive/angry/contentious, I apologize.
psychgirl
Has No Life - Lives on TB
SouthernBreeze
Has No Life - Lives on TB
I see nothing wrong with giving the daily number of cases each day. I also see nothing wrong with giving the percentage of those numbers based on the world's population. It gives us a baseline to go by. Fact says that it's still a small percentage, but as you stated, it has the possibility to get much worse over time. I see both numbers as being helpful as we continue to watch.
If only they were trustworthy numbers ....
SouthernBreeze
Has No Life - Lives on TB
Let me also say this. I've been with this thread from the first post. I see 2 groups of people here.
1. There are those who want to laugh this off as being a hoax or a make believe fantasy made up by our government. A subset of those believe it is only for gay people, and no one else has anything to worry about.
2. There are those who know and believe that this is a dangerous disease that may have implications for all of us. It's very important to know the facts and pay attention, so we can be prepared if the need arises.
Lets not turn the thread into an open conflict based on our differences of opinions.
1. There are those who want to laugh this off as being a hoax or a make believe fantasy made up by our government. A subset of those believe it is only for gay people, and no one else has anything to worry about.
2. There are those who know and believe that this is a dangerous disease that may have implications for all of us. It's very important to know the facts and pay attention, so we can be prepared if the need arises.
Lets not turn the thread into an open conflict based on our differences of opinions.
phloydius
Veteran Member
View: https://twitter.com/RolandBakerIII/status/1554572947565645824
Roland Baker 2.0
@RolandBakerIII
In the WHO report today if we break out hospitalization rates they are 6.53% for MSM and 19.2% for non-MSM or about 300% higher. We can only guess that this is an artifact of testing bias with less severe cases in non-MSM not being tested.
Roland Baker 2.0
@RolandBakerIII
In the WHO report today if we break out hospitalization rates they are 6.53% for MSM and 19.2% for non-MSM or about 300% higher. We can only guess that this is an artifact of testing bias with less severe cases in non-MSM not being tested.
Meemur
Voice on the Prairie / FJB!
Thank you! Well said.
And I've been trying to do better about that, both here and on other threads.
SouthernBreeze
Has No Life - Lives on TB
Me, too.
bw
Fringe Ranger
But if you keep blurting out random pronouncements like I do, every now and then you'll get one right.
SouthernBreeze
Has No Life - Lives on TB
psychgirl
Has No Life - Lives on TB
“Quarantine site”…..I’m not fond of those words.
Too close… for comfort
Meemur
Voice on the Prairie / FJB!
I'm sure I'm not the only one who is hearing increased talk of home schooling or continuing to home school this fall.
SouthernBreeze
Has No Life - Lives on TB
Well doz. I always sit up and pay attention to your opinions.
somewherepress
Has No Life - Lives on TB
NEW ZEALAND HEALTH
6:43 am today
Monkeypox: 'A short window of opportunity to act' - Experts push for stronger response
6:43 am today
Jake McKee, reporter
@journjake jake.mckee@rnz.co.nz
Leading health advocates are pleading for bolder action on monkeypox, saying New Zealand could see the same failures as other countries if the government doesn't act now.
There is concern New Zealand is not learning fast enough from the experience of other countries on handling monkeypox. Photo: AFP / Joao Luiz Bulcao / Hans Lucas
A five-page letter has been sent to Prime Minister Jacinda Ardern, with a range of government ministers and health officials copied in, including Minister of Health Andrew Little, Associate Minister of Health Ayesha Verrall, and top staff from Health New Zealand and the Māori Health Authority.
It calls for "urgent action to prepare for and prevent the escalation of MPX [monkeypox] cases in Aotearoa New Zealand", and is signed by Burnett Foundation (formerly the NZ Aids Foundation) chief executive Joe Rich, New Zealand Sexual Health Society president Anne Robertson, and top sexual health researcher Peter Saxton.
"We must act now," they wrote. "The rapid spread of MPX indicates a failure of the public health strategies that were implemented early on overseas."
They want a dedicated monkeypox response team; a vaccine plan prioritised; better, stigma-free, public health communication; and support for self-isolation.
Rich told RNZ the organisation had been constructively working with the government on a response but was concerned how similar current plans were to those of Northern Hemisphere countries.
"What we're seeing at the moment is that in the Northern Hemisphere, the approaches that they've been using to try and control monkeypox have not been working and the [case] numbers are increasing."
Since early May, more than 18,000 cases have been confirmed or suspected in more than 70 countries outside of where the virus was usually endemic.
In New Zealand, three cases have been confirmed - two of whom have recovered. The Ministry of Health considers the public health risk to be low-to-moderate, but with a high risk of more cases being imported.
Rich said a post-exposure vaccine approach, known as ring vaccination, was "not going to be enough" and that it should instead be pre-emptive and used as a primary tool instead of relying on contact tracing and testing.
"This is not a criticism," he said. "This is just saying that we have the advantage ... of being able to learn about what is or isn't working in other countries."
University of Auckland associate professor Peter Saxton said procuring pre-exposure vaccines was needed so New Zealand could "stay ahead of the virus, rather than chasing an infection that we see moving fast among most at-risk communities overseas".
He was concerned that infections would soon start being missed and the virus would "start spreading locally".
"We still have a short window of opportunity to act before monkeypox becomes established."
The Ministry of Health said it was "working with Pharmac to secure access to third generation smallpox vaccines that can be considered for the targeted prevention of monkeypox".
RNZ understands health officials and manufacturers are discussing a possible delivery schedule for a vaccine, as well as antiretroviral treatments.
Joe Rich, left, and Peter Saxton are among those conveying their concerns to the government. Photo: RNZ / Jake McKee
'I'm quite worried to be honest with you'
Gay, bisexual and other men who have sex with men (MSM) have been disproportionately affected in the current global outbreak but anyone can be infected with monkeypox.
The Ministry of Health said the risk of transmission was "considerably lower" than Covid-19 or measles, "given it requires very close contact".
It could be transmitted person-to-person by close contact with skin lesions, body fluids, respiratory droplets and contaminated materials such as bedding, but was not likely to be a sexually transmitted infection.
Dr Massimo Giola. Photo: Supplied
Dr Massimo Giola, is a member of the New Zealand Sexual Health Society executive, said the country needed to act "before we have a major problem in our hands".
Dr Giola is gay and studied infectious disease in Italy, during the 1990s, "right at the top of the AIDs pandemic". The current monkeypox outbreak made him feel like he was reliving that time but in "fast forward" and he wanted to see a stronger outbreak response.
He said he understood why some MSM "feel under threat".
"I'm quite worried to be honest with you."
There were challenges in creating a response without stigma, Giola said.
Specifically, officials needed to carefully juggle acknowledging the disproportionate rate at which the MSM community was being affected without stoking the homophobia that the outbreak had stirred up online, including people calling monkeypox a "gay disease" or thinking it only affected the MSM community, he said.
The struggle of this was already coming through in patients he saw. Giola had started talking to patients enquiring about HIV-prevention drug PrEP whether they knew of monkeypox and where to find information.
"Always, always, always the question I get is: 'when are we getting the vaccine?' So people are very aware there is a vaccine and they definitely want to have access to that."
'Leadership, bold action' needed
The Burnett Foundation's Rich said they were not trying to create panic but officials needed to be "very careful" to get the response right.
"We know from our experience with Covid we have unique opportunities in New Zealand to learn from the rest of the world."
Similarities to the Covid-19 pandemic response were mentioned in the letter to Ardern.
"As with Covid-19, an effective response to MPX requires leadership, bold action, and comprehensive resourcing at a level commensurate with the threat of this novel global public health emergency."
RNZ asked the Ministry of Health a series of specific questions about the concerns raised in the letter.
They went unanswered, but the acting public health director, Harriette Carr, said the ministry "acknowledge the concerns raised in this letter".
Carr also said public health advice had been worked on since "the early stages of the current global outbreak" for the general public and health professionals.
RNZ has also approached the offices of the prime minister, minister of health, and associate health minister for comment.
6:43 am today
Monkeypox: 'A short window of opportunity to act' - Experts push for stronger response
6:43 am today
Jake McKee, reporter
@journjake jake.mckee@rnz.co.nz
Leading health advocates are pleading for bolder action on monkeypox, saying New Zealand could see the same failures as other countries if the government doesn't act now.
There is concern New Zealand is not learning fast enough from the experience of other countries on handling monkeypox. Photo: AFP / Joao Luiz Bulcao / Hans Lucas
A five-page letter has been sent to Prime Minister Jacinda Ardern, with a range of government ministers and health officials copied in, including Minister of Health Andrew Little, Associate Minister of Health Ayesha Verrall, and top staff from Health New Zealand and the Māori Health Authority.
It calls for "urgent action to prepare for and prevent the escalation of MPX [monkeypox] cases in Aotearoa New Zealand", and is signed by Burnett Foundation (formerly the NZ Aids Foundation) chief executive Joe Rich, New Zealand Sexual Health Society president Anne Robertson, and top sexual health researcher Peter Saxton.
"We must act now," they wrote. "The rapid spread of MPX indicates a failure of the public health strategies that were implemented early on overseas."
They want a dedicated monkeypox response team; a vaccine plan prioritised; better, stigma-free, public health communication; and support for self-isolation.
Rich told RNZ the organisation had been constructively working with the government on a response but was concerned how similar current plans were to those of Northern Hemisphere countries.
"What we're seeing at the moment is that in the Northern Hemisphere, the approaches that they've been using to try and control monkeypox have not been working and the [case] numbers are increasing."
Since early May, more than 18,000 cases have been confirmed or suspected in more than 70 countries outside of where the virus was usually endemic.
In New Zealand, three cases have been confirmed - two of whom have recovered. The Ministry of Health considers the public health risk to be low-to-moderate, but with a high risk of more cases being imported.
Rich said a post-exposure vaccine approach, known as ring vaccination, was "not going to be enough" and that it should instead be pre-emptive and used as a primary tool instead of relying on contact tracing and testing.
"This is not a criticism," he said. "This is just saying that we have the advantage ... of being able to learn about what is or isn't working in other countries."
University of Auckland associate professor Peter Saxton said procuring pre-exposure vaccines was needed so New Zealand could "stay ahead of the virus, rather than chasing an infection that we see moving fast among most at-risk communities overseas".
He was concerned that infections would soon start being missed and the virus would "start spreading locally".
"We still have a short window of opportunity to act before monkeypox becomes established."
The Ministry of Health said it was "working with Pharmac to secure access to third generation smallpox vaccines that can be considered for the targeted prevention of monkeypox".
RNZ understands health officials and manufacturers are discussing a possible delivery schedule for a vaccine, as well as antiretroviral treatments.
Joe Rich, left, and Peter Saxton are among those conveying their concerns to the government. Photo: RNZ / Jake McKee
'I'm quite worried to be honest with you'
Gay, bisexual and other men who have sex with men (MSM) have been disproportionately affected in the current global outbreak but anyone can be infected with monkeypox.
The Ministry of Health said the risk of transmission was "considerably lower" than Covid-19 or measles, "given it requires very close contact".
It could be transmitted person-to-person by close contact with skin lesions, body fluids, respiratory droplets and contaminated materials such as bedding, but was not likely to be a sexually transmitted infection.
Dr Massimo Giola. Photo: Supplied
Dr Massimo Giola, is a member of the New Zealand Sexual Health Society executive, said the country needed to act "before we have a major problem in our hands".
Dr Giola is gay and studied infectious disease in Italy, during the 1990s, "right at the top of the AIDs pandemic". The current monkeypox outbreak made him feel like he was reliving that time but in "fast forward" and he wanted to see a stronger outbreak response.
He said he understood why some MSM "feel under threat".
"I'm quite worried to be honest with you."
There were challenges in creating a response without stigma, Giola said.
Specifically, officials needed to carefully juggle acknowledging the disproportionate rate at which the MSM community was being affected without stoking the homophobia that the outbreak had stirred up online, including people calling monkeypox a "gay disease" or thinking it only affected the MSM community, he said.
The struggle of this was already coming through in patients he saw. Giola had started talking to patients enquiring about HIV-prevention drug PrEP whether they knew of monkeypox and where to find information.
"Always, always, always the question I get is: 'when are we getting the vaccine?' So people are very aware there is a vaccine and they definitely want to have access to that."
'Leadership, bold action' needed
The Burnett Foundation's Rich said they were not trying to create panic but officials needed to be "very careful" to get the response right.
"We know from our experience with Covid we have unique opportunities in New Zealand to learn from the rest of the world."
Similarities to the Covid-19 pandemic response were mentioned in the letter to Ardern.
"As with Covid-19, an effective response to MPX requires leadership, bold action, and comprehensive resourcing at a level commensurate with the threat of this novel global public health emergency."
RNZ asked the Ministry of Health a series of specific questions about the concerns raised in the letter.
They went unanswered, but the acting public health director, Harriette Carr, said the ministry "acknowledge the concerns raised in this letter".
Carr also said public health advice had been worked on since "the early stages of the current global outbreak" for the general public and health professionals.
RNZ has also approached the offices of the prime minister, minister of health, and associate health minister for comment.
somewherepress
Has No Life - Lives on TB
I did a search and there are no reported cases of Monkeypox at any daycare center in Delaware (or anywhere else in the country) . Do you have a legitimate news source for this?
Doesn't matter. Vaccina for smallpox is only effective for 3-5 years. Its not lifetime immunity.
somewherepress
Has No Life - Lives on TB
Immunity from smallpox vaccine persists for decades: a longitudinal study - PubMed
These data suggest that multiple or recent vaccinations are not essential to maintain vaccinia-specific antibody responses in human subjects. Scarce vaccine supplies should be applied first to individuals who have not previously been vaccinated.
pubmed.ncbi.nlm.nih.gov
Not everyone shares your 3-5 year viewpoint.
Am J Med
. 2008 Dec;121(12):1058-64.
doi: 10.1016/j.amjmed.2008.08.019.
Immunity from smallpox vaccine persists for decades: a longitudinal study
Dennis D Taub 1, William B Ershler, Mark Janowski, Andrew Artz, Michael L Key, Julie McKelvey, Denis Muller, Bernard Moss, Luigi Ferrucci, Patricia L Duffey, Dan L Longo
Affiliations expand
- PMID: 19028201
- PMCID: PMC2610468
- DOI: 10.1016/j.amjmed.2008.08.019
Abstract
Purpose: The threat of smallpox resulting from bioterrorist action has prompted a reassessment of the level of immunity in current populations.
Methods: We have examined the magnitude and duration of antiviral antibody immunity conferred by smallpox vaccination in 246 participants of the Baltimore Longitudinal Study of Aging. Of this population, 209 subjects were vaccinated one or more times 13 to 88 years before this evaluation, and stored serum samples were available at various intervals after vaccination. An additional 8 subjects who had documented childhood smallpox infection and 29 subjects with no history of infection or vaccination were included. We quantified the total vaccinia IgG and neutralizing antibody titers in each of these subgroups of participants over time.
Results: Vaccinated participants maintained antivaccinia IgG and neutralizing antibody titers above 3 natural logs essentially indefinitely. The absolute titer of antivaccinia antibody was only slightly higher after multiple vaccinations. In 97% of the participants, no decrease in vaccinia-specific antibody titers was noted with age over a follow-up period of up to 88 years. Moreover, Baltimore Longitudinal Study of Aging participants who survived active smallpox infections in their youth retained antivaccinia antibody titers that were similar to the levels detected in vaccinated subjects.
Conclusion: These data suggest that multiple or recent vaccinations are not essential to maintain vaccinia-specific antibody responses in human subjects. Scarce vaccine supplies should be applied first to individuals who have not previously been vaccinated.
Last edited:
Immunity from smallpox vaccine persists for decades: a longitudinal study - PubMed
These data suggest that multiple or recent vaccinations are not essential to maintain vaccinia-specific antibody responses in human subjects. Scarce vaccine supplies should be applied first to individuals who have not previously been vaccinated.
Not everyone shares your 3-5 year viewpoint.
Am J Med
. 2008 Dec;121(12):1058-64.
doi: 10.1016/j.amjmed.2008.08.019.
Immunity from smallpox vaccine persists for decades: a longitudinal study
Dennis D Taub 1, William B Ershler, Mark Janowski, Andrew Artz, Michael L Key, Julie McKelvey, Denis Muller, Bernard Moss, Luigi Ferrucci, Patricia L Duffey, Dan L Longo
Affiliations expand
Free PMC article
- PMID: 19028201
- PMCID: PMC2610468
- DOI: 10.1016/j.amjmed.2008.08.019
Abstract
Purpose: The threat of smallpox resulting from bioterrorist action has prompted a reassessment of the level of immunity in current populations.
Methods: We have examined the magnitude and duration of antiviral antibody immunity conferred by smallpox vaccination in 246 participants of the Baltimore Longitudinal Study of Aging. Of this population, 209 subjects were vaccinated one or more times 13 to 88 years before this evaluation, and stored serum samples were available at various intervals after vaccination. An additional 8 subjects who had documented childhood smallpox infection and 29 subjects with no history of infection or vaccination were included. We quantified the total vaccinia IgG and neutralizing antibody titers in each of these subgroups of participants over time.
Results: Vaccinated participants maintained antivaccinia IgG and neutralizing antibody titers above 3 natural logs essentially indefinitely. The absolute titer of antivaccinia antibody was only slightly higher after multiple vaccinations. In 97% of the participants, no decrease in vaccinia-specific antibody titers was noted with age over a follow-up period of up to 88 years. Moreover, Baltimore Longitudinal Study of Aging participants who survived active smallpox infections in their youth retained antivaccinia antibody titers that were similar to the levels detected in vaccinated subjects.
Conclusion: These data suggest that multiple or recent vaccinations are not essential to maintain vaccinia-specific antibody responses in human subjects. Scarce vaccine supplies should be applied first to individuals who have not previously been vaccinated.
Small study but I really laughed at the end comments....
We thank Drs. Anthony Fauci and David Schlessinger for their helpful comments and careful review of this manuscript. In addition, we thank Dr. Dorothy Scott (CBER/FDA) for her assistance in obtaining the VIG reference standard.
I wondered how long it would take for this to get reported......
More and more this rolling fiasco is reminding me of the beginnings of the AIDS outbreak and the politically directed blind eyes directed to the main population at risk and spreading it to everyone else.
psychgirl
Has No Life - Lives on TB
psychgirl
Has No Life - Lives on TB
I’ve not had time to look, myself. I’ll try to.
Been working since 6:30 am, today.
somewherepress
Has No Life - Lives on TB
I notice you deflected rather than choosing to respond to the "small study" conclusion.
You can keep laughing.
But here's a piece from a couple weeks ago, that further refutes your promotion of the idea that smallpox vax needs to be renewed every 3-5 years and adds that you may be protected from Monkeypox as well if you had the original dose..
Adults with smallpox vaccine may have immunity from monkeypox
connect.uclahealth.org
Adults with smallpox vaccine may have immunity from monkeypox
By Ask the Doctors • July 25, 2022
Share this:
Dear Doctors: How long does the smallpox vaccine stay effective? I ask because I received it as a child in the 1950s. Is it known if the vaccine would be effective against monkeypox some 60 years later, or is a booster needed? Does a booster even exist?
Dear Reader: With cases of monkeypox spreading throughout the world, concern about this rare virus is growing. The disease, which is endemic to central and west Africa, began to appear in Europe and the United States in May. Since that time, the U.S. has recorded more than 350 cases. Yet health officials warn that, due to unfamiliarity with the disease and limited testing, the actual number of cases in this country is likely higher. We’ve discussed this outbreak before, but with cases on the rise, we think a recap is wise.
Monkeypox is related to smallpox, but the disease that it causes is not as severe. For the majority of people who become infected, symptoms are similar to those of the flu. That includes fever, chills, headache, body aches, swollen lymph nodes and fatigue. In more severe cases, patients develop a distinctive rash and lesions, most often on the hands, the face and the soles of the feet.
Monkeypox is not known to linger in the air, and it is not transmitted during brief periods of shared airspace. Instead, the disease most often spreads through direct physical contact with an infected individual, or with their bodily fluids. Because sores may be inside the body, including the mouth, vagina or anus, sexual transmission is possible. The virus can also be spread by contact with items that have touched either the infectious rash or bodily fluids, such as linens or clothing.
An infected individual is contagious from the moment symptoms begin. Those who develop a rash or lesions can continue to spread the disease until the rash has healed completely and is covered by a fresh layer of skin.
Adults like yourself who received the smallpox vaccine during the nationwide program that was in effect from the late 1940s until 1972 are believed to have continuing immunity. This includes members of the U.S. military, who continued to receive smallpox vaccinations until 1991.
The Centers for Disease Control and Prevention says that, based on past data collected in Africa, the smallpox vaccine is at least 85% effective in preventing monkeypox. However, since this situation is so new, the precise degree of protection is not known. Researchers say that while older adults who have been vaccinated against smallpox may be susceptible to monkeypox infection, they are likely to experience only mild symptoms. The data show that the majority of healthy adults who become infected do not become severely ill. And to your question about smallpox boosters, no, they are not available.
To combat this outbreak, the U.S. has just purchased 2.5 million doses of monkeypox vaccine, which bolsters the 500,000 doses already stockpiled. Distribution to high-risk individuals is expected to begin soon. You can find detailed information about smallpox and monkeypox at the CDC website. Visit cdc.gov/poxvirus and click the appropriate link.
Our infectious disease specialists are experts in patient care, research and education. We assist many teams throughout UCLA Health, provide outpatient care and have global reach through our specialized programs.
psychgirl
Has No Life - Lives on TB
Thank you for this.I notice you deflected rather than choosing to respond to the "small study" conclusion.
You can keep laughing.
But here's a piece from a couple weeks ago, that further refutes your promotion of the idea that smallpox vax needs to be renewed every 3-5 years and adds that you may be protected from Monkeypox as well if you had the original dose..
Adults with smallpox vaccine may have immunity from monkeypox
Adults with smallpox vaccine may have immunity from monkeypox
By Ask the Doctors • July 25, 2022
Share this:
Dear Doctors: How long does the smallpox vaccine stay effective? I ask because I received it as a child in the 1950s. Is it known if the vaccine would be effective against monkeypox some 60 years later, or is a booster needed? Does a booster even exist?
Dear Reader: With cases of monkeypox spreading throughout the world, concern about this rare virus is growing. The disease, which is endemic to central and west Africa, began to appear in Europe and the United States in May. Since that time, the U.S. has recorded more than 350 cases. Yet health officials warn that, due to unfamiliarity with the disease and limited testing, the actual number of cases in this country is likely higher. We’ve discussed this outbreak before, but with cases on the rise, we think a recap is wise.
Monkeypox is related to smallpox, but the disease that it causes is not as severe. For the majority of people who become infected, symptoms are similar to those of the flu. That includes fever, chills, headache, body aches, swollen lymph nodes and fatigue. In more severe cases, patients develop a distinctive rash and lesions, most often on the hands, the face and the soles of the feet.
Monkeypox is not known to linger in the air, and it is not transmitted during brief periods of shared airspace. Instead, the disease most often spreads through direct physical contact with an infected individual, or with their bodily fluids. Because sores may be inside the body, including the mouth, vagina or anus, sexual transmission is possible. The virus can also be spread by contact with items that have touched either the infectious rash or bodily fluids, such as linens or clothing.
An infected individual is contagious from the moment symptoms begin. Those who develop a rash or lesions can continue to spread the disease until the rash has healed completely and is covered by a fresh layer of skin.
Elizabeth Ko, MD and Eve Glazier, MD
Adults like yourself who received the smallpox vaccine during the nationwide program that was in effect from the late 1940s until 1972 are believed to have continuing immunity. This includes members of the U.S. military, who continued to receive smallpox vaccinations until 1991.
The Centers for Disease Control and Prevention says that, based on past data collected in Africa, the smallpox vaccine is at least 85% effective in preventing monkeypox. However, since this situation is so new, the precise degree of protection is not known. Researchers say that while older adults who have been vaccinated against smallpox may be susceptible to monkeypox infection, they are likely to experience only mild symptoms. The data show that the majority of healthy adults who become infected do not become severely ill. And to your question about smallpox boosters, no, they are not available.
To combat this outbreak, the U.S. has just purchased 2.5 million doses of monkeypox vaccine, which bolsters the 500,000 doses already stockpiled. Distribution to high-risk individuals is expected to begin soon. You can find detailed information about smallpox and monkeypox at the CDC website. Visit cdc.gov/poxvirus and click the appropriate link.
Our infectious disease specialists are experts in patient care, research and education. We assist many teams throughout UCLA Health, provide outpatient care and have global reach through our specialized programs.
I notice you deflected rather than choosing to respond to the "small study" conclusion.
You can keep laughing.
But here's a piece from a couple weeks ago, that further refutes your promotion of the idea that smallpox vax needs to be renewed every 3-5 years and adds that you may be protected from Monkeypox as well if you had the original dose..
Adults with smallpox vaccine may have immunity from monkeypox
Adults with smallpox vaccine may have immunity from monkeypox
By Ask the Doctors • July 25, 2022
Share this:
Dear Doctors: How long does the smallpox vaccine stay effective? I ask because I received it as a child in the 1950s. Is it known if the vaccine would be effective against monkeypox some 60 years later, or is a booster needed? Does a booster even exist?
Dear Reader: With cases of monkeypox spreading throughout the world, concern about this rare virus is growing. The disease, which is endemic to central and west Africa, began to appear in Europe and the United States in May. Since that time, the U.S. has recorded more than 350 cases. Yet health officials warn that, due to unfamiliarity with the disease and limited testing, the actual number of cases in this country is likely higher. We’ve discussed this outbreak before, but with cases on the rise, we think a recap is wise.
Monkeypox is related to smallpox, but the disease that it causes is not as severe. For the majority of people who become infected, symptoms are similar to those of the flu. That includes fever, chills, headache, body aches, swollen lymph nodes and fatigue. In more severe cases, patients develop a distinctive rash and lesions, most often on the hands, the face and the soles of the feet.
Monkeypox is not known to linger in the air, and it is not transmitted during brief periods of shared airspace. Instead, the disease most often spreads through direct physical contact with an infected individual, or with their bodily fluids. Because sores may be inside the body, including the mouth, vagina or anus, sexual transmission is possible. The virus can also be spread by contact with items that have touched either the infectious rash or bodily fluids, such as linens or clothing.
An infected individual is contagious from the moment symptoms begin. Those who develop a rash or lesions can continue to spread the disease until the rash has healed completely and is covered by a fresh layer of skin.
Elizabeth Ko, MD and Eve Glazier, MD
Adults like yourself who received the smallpox vaccine during the nationwide program that was in effect from the late 1940s until 1972 are believed to have continuing immunity. This includes members of the U.S. military, who continued to receive smallpox vaccinations until 1991.
The Centers for Disease Control and Prevention says that, based on past data collected in Africa, the smallpox vaccine is at least 85% effective in preventing monkeypox. However, since this situation is so new, the precise degree of protection is not known. Researchers say that while older adults who have been vaccinated against smallpox may be susceptible to monkeypox infection, they are likely to experience only mild symptoms. The data show that the majority of healthy adults who become infected do not become severely ill. And to your question about smallpox boosters, no, they are not available.
To combat this outbreak, the U.S. has just purchased 2.5 million doses of monkeypox vaccine, which bolsters the 500,000 doses already stockpiled. Distribution to high-risk individuals is expected to begin soon. You can find detailed information about smallpox and monkeypox at the CDC website. Visit cdc.gov/poxvirus and click the appropriate link.
Our infectious disease specialists are experts in patient care, research and education. We assist many teams throughout UCLA Health, provide outpatient care and have global reach through our specialized programs.
I responded to it as a "small study" because you typically don't make public health decisions on a study with an N of 200 some odd patients. Guidelines are for 3-5 years if high risk as titers fall after 3 years.
Here is the guidelines for the 3 vaccines:
note here:
Survivors of smallpox appeared to have lifelong protection from reinfection with the virus (1,23). In contrast, vaccine-induced immunity was most effective in the first 1–3 years following vaccination, and complete protection was not lifelong (1). Effectiveness of vaccine approached 100% when administered before exposure occurred, and substantial protection might have endured for up to 15–20 years (1,12,24,25). Even when administered postexposure, vaccination against smallpox appeared to have been effective in preventing and/or ameliorating disease when administered to contacts of patients with smallpox. Such postexposure prophylaxis is believed to have been most effective when administered as soon as possible following viral exposure, particularly in previously vaccinated persons capable of mounting an anamnestic response. Data from the eradication era suggest that vaccination >3 days after exposure to the virus was less effective but might still have decreased morbidity and mortality (26–29).
and yeah, the smallpox vaccine has cross reactivity with a number of the pox viruses.
I am encouraged that you are starting to accept studies from NIH, CDC and the like. Progress of a sort.
somewherepress
Has No Life - Lives on TB
I responded to it as a "small study" because you typically don't make public health decisions on a study with an N of 200 some odd patients. Guidelines are for 3-5 years if high risk as titers fall after 3 years.
Here is the guidelines for the 3 vaccines:
note here:
Survivors of smallpox appeared to have lifelong protection from reinfection with the virus (1,23). In contrast, vaccine-induced immunity was most effective in the first 1–3 years following vaccination, and complete protection was not lifelong (1). Effectiveness of vaccine approached 100% when administered before exposure occurred, and substantial protection might have endured for up to 15–20 years (1,12,24,25). Even when administered postexposure, vaccination against smallpox appeared to have been effective in preventing and/or ameliorating disease when administered to contacts of patients with smallpox. Such postexposure prophylaxis is believed to have been most effective when administered as soon as possible following viral exposure, particularly in previously vaccinated persons capable of mounting an anamnestic response. Data from the eradication era suggest that vaccination >3 days after exposure to the virus was less effective but might still have decreased morbidity and mortality (26–29).
and yeah, the smallpox vaccine has cross reactivity with a number of the pox viruses.
I am encouraged that you are starting to accept studies from NIH, CDC and the like. Progress of a sort.
It's quite peculiar that you are encouraged by a conclusion that is purely a figment of your imagination.
Your bias concerning continuing smallpox vaccine efficacy is noted.
And many genuine experts disagree with your assessment.
Perhaps you'd like to address the conclusions from the small study and the guidance found in the July 25,2022 piece from UCLA rather than deflect and reference an obscure CDC quote from 2015.
From post 4351
Results: Vaccinated participants maintained antivaccinia IgG and neutralizing antibody titers above 3 natural logs essentially indefinitely. The absolute titer of antivaccinia antibody was only slightly higher after multiple vaccinations. In 97% of the participants, no decrease in vaccinia-specific antibody titers was noted with age over a follow-up period of up to 88 years. Moreover, Baltimore Longitudinal Study of Aging participants who survived active smallpox infections in their youth retained antivaccinia antibody titers that were similar to the levels detected in vaccinated subjects.
Conclusion: These data suggest that multiple or recent vaccinations are not essential to maintain vaccinia-specific antibody responses in human subjects. Scarce vaccine supplies should be applied first to individuals who have not previously been vaccinated.
From Post 4356
Adults like yourself who received the smallpox vaccine during the nationwide program that was in effect from the late 1940s until 1972 are believed to have continuing immunity. This includes members of the U.S. military, who continued to receive smallpox vaccinations until 1991.
The Centers for Disease Control and Prevention says that, based on past data collected in Africa, the smallpox vaccine is at least 85% effective in preventing monkeypox. However, since this situation is so new, the precise degree of protection is not known. Researchers say that while older adults who have been vaccinated against smallpox may be susceptible to monkeypox infection, they are likely to experience only mild symptoms. The data show that the majority of healthy adults who become infected do not become severely ill. And to your question about smallpox boosters, no, they are not available.
I see nothing wrong with tracking this. If it’s nothing it will fizzle out. If it is something, then we have a 1-2 month jump on it.
Same thing with Covid. People here were posting pics, and Twitter posts coming out of China a full 2 months before news broke here.
Nothing wrong with watching to see where this goes.
Same thing with Covid. People here were posting pics, and Twitter posts coming out of China a full 2 months before news broke here.
Nothing wrong with watching to see where this goes.